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DRUG DISCOVERY SERVICES BINDING CHARACTERIZATION PROCESS

Low Risk, High-Value Target-Ligand Binding Characterization Process

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DIFFICULT, MIND-BENDING TARGETS

Our experienced scientists, armed with TruBind technology, eagerly tackle complex, technically challenging, high-value targets where small molecule binding has proven intractable by other techniques. Set the bar high and we’ll meet the challenge!

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ASSAY DEVELOPMENT & VALIDATION

We’ll quickly arrive at a fast yes or no answer on appropriate control binding. If the answer is yes, we will produce a validated assay, all in a couple of weeks. Now you can confidently move forward with further assay investment. Here’s to a possible huge upside!

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CHARACTERIZE TARGET-COMPOUND BINDING

Next, let’s answer critical questions related to the characterization of a small number of key compounds using the Phase 1 assay to help drive your drug discovery project forward. Start gathering all the great data for your IND submission!

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INTEGRATION OF TRUBIND ASSAY & SYSTEM

When you buy your first TruBind Integrated Solution, we’ll transfer your successful Phase 1 assay, you’ll recoup your Phase 1 investment via reduced instrument pricing, and you’ll receive very attentive support. Let the accolades begin!

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ON-GOING CUSTOMIZED PROJECT SUPPORT

Let us speed your discovery process by addressing multiple compound series and targets in parallel. Or we can undertake deeper MoA and target-compound characterization for medchem and pharmacology decision-making. Let us do the heavy lifting!

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EVEN MORE DIFFICULT, MIND-BENDING TARGETS

Challenge us again with your most complex and intractable targets such as GPCRs, ion-channels, RTKs, PPIs, transcription factors, fibrils, contractile proteins, and more. Let us go again where others fear to tread!

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Your drug discovery research progress can be accelerated exponentially as we help you:
  • • Address multiple compounds and targets in parallel
  • • Undertake deeper MOA and target-compound characterization
  • • Guide medchem and pharmacology decision making

 


 

READ ABOUT OUR TESTED SOLUTIONS BY WORLD CLASS PHARMACEUTICAL CLIENTS>

 

DRUG DISCOVERY SERVICES

  • ASSAY DEVELOPMENT
  • SECONDARY SCREENING
  • BINDING CHARACTERIZATION PROCESS
  • PHARMACEUTICAL PROJECTS

ON-DEMAND WEBINARS

  • Interrogating Ligand: Target Interactions Using Back-Scattering Interferometry Yields Mechanistic Insight and Aids in Compound PrioritizationBy MSI on January 26, 2016
  • Review of Recent Publications Featuring Binding Data Produced by MSIBy MSI on January 26, 2016
  • Conformation-Sensitive Assay Detection for Accelerated Drug Discovery ResearchBy MSI on February 10, 2015
  • Evaluation of the MoA of Allosteric Modulators and Its Application to Drug Discovery using Back-Scattering InterferometryBy MSI on November 13, 2014
  • Using BSI to Investigate Positive Allosteric Modulators of the M4 ReceptorBy MSI on September 3, 2014

Read about our low-risk, high-value Target-Ligand Binding Characterization Process that a majority of the top ten pharmaceutical and biotechnology companies have used to solve drug binding characterization problems impacting early discovery through IND submission.

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