Molecular Sensing, Inc. is launching a breakthrough molecular interaction technology for drug discovery.
Back-Scattering Interferometry (BSI) enables:
Label-free, in solution Kd measurements eliminating both immobilization and target molecule labeling.
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Unprecedented sensitivity and Kd dynamic range for small molecule — large protein binding compared to SPR and ITC.
Analyze binding equilibrium Kd's from pM to mM in complex matrices — serum, DMSO, cell lysates, impure mixtures and cell membrane preparations.
Use of small quantities (nanomoles) and volumes (10 µL) of protein radically reducing target protein development and manufacturing cost.
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MSI is currently working toward commercial launch of the first BSI instrument for drug discovery and biotherapeutic research. Immediate access to the technology is available through a service based Life-science Early Access Program (LEAP).
Please contact us if you have a critical need to improve:
Biophysical profiling of drug candidate
Lead optimization assay
Medicinal chemistry drug optimization
Secondary screening
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Label free assays
- Membrane-ligand
- GPCR'S
- Inhibitor-target
- Protein-protein
- Ab-Ag
- Protein-DNA
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Measurement of pM to mM Kd's
Binding studies in impure mixtures
Characterize binding under native
physiological conditions
Assess promiscuous binders
Reduce protein target quantities
Correlation of cell-based assays
to target binding assays
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